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Anti-SLAMF6/LY108 Polyclonal Antibody

Catalog No. TMAB-12830 Copy Product Info
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Anti-SLAMF6/LY108 Polyclonal Antibody is a Rabbit antibody targeting SLAMF6/LY108. Anti-SLAMF6/LY108 Polyclonal Antibody can be used in WB.

Anti-SLAMF6/LY108 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12830

Anti-SLAMF6/LY108 Polyclonal Antibody is a Rabbit antibody targeting SLAMF6/LY108. Anti-SLAMF6/LY108 Polyclonal Antibody can be used in WB.

Anti-SLAMF6/LY108 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SLAMF6/LY108 Polyclonal Antibody is a Rabbit antibody targeting SLAMF6/LY108. Anti-SLAMF6/LY108 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Rat)
Verified Activity
Sample: Lymph node (Mouse) Lysate at 40 μg
Primary: Anti-LY108 (TMAB-12830) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 48 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein (Probable).
Tissue SpecificityExpressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse SLAMF6
Antigen Species
Mouse
Gene Name
SLAMF6
Gene ID
Protein Name
SLAM family member 6
Uniprot ID
Function
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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