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Anti-5HT2B Receptor Polyclonal Antibody 2 (Synonyms: Stomach fundus serotonin receptor, SR-2B, Serotonin recep...)

Catalog No. TMAB-02104 Copy Product Info
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Anti-5HT2B Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT2B Receptor. Anti-5HT2B Receptor Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.

Anti-5HT2B Receptor Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-02104
Synonyms Stomach fundus serotonin receptor, SR-2B, Serotonin receptor 2B, SEROTONIN 5HT2B RECEPTOR, NP75 protein, Htr2b, Htr 2b, 5-hydroxytryptamine receptor 2B, 5HT2F, 5HT2B_HUMAN, 5-HT-2B, 5-HT2B, 5HT(2B), 5 hydroxytryptamine(serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine(serotonin) receptor 2B, 5 hydroxytryptamine receptor 2B, 5 hydroxytryptamine 2B receptor, 5 HT2B, 5 HT(2B), 5 HT 2B receptor, 5 HT 2B

Anti-5HT2B Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT2B Receptor. Anti-5HT2B Receptor Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.

Anti-5HT2B Receptor Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-5HT2B Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT2B Receptor. Anti-5HT2B Receptor Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
SynonymsStomach fundus serotonin receptor, SR-2B, Serotonin receptor 2B, SEROTONIN 5HT2B RECEPTOR, NP75 protein, Htr2b, Htr 2b, 5-hydroxytryptamine receptor 2B, 5HT2F, 5HT2B_HUMAN, 5-HT-2B, 5-HT2B, 5HT(2B), 5 hydroxytryptamine(serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine(serotonin) receptor 2B, 5 hydroxytryptamine receptor 2B, 5 hydroxytryptamine 2B receptor, 5 HT2B, 5 HT(2B), 5 HT 2B receptor, 5 HT 2B
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (5HT2B Receptor) Polyclonal Antibody, Unconjugated (TMAB-02104) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human SH-SY5Y cell lysates
Lane 3: Human MCF-7 cell lysates
Lane 4: Human HeLa cell lysates
Primary: Anti-5HT2B Receptor (TMAB-02104) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 60 kDa
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
Tissue SpecificityExpressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMultiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 5HT2B Receptor/SR-2B
Antigen Species
Human
Gene Name
HTR2B
Gene ID
Protein Name
5-hydroxytryptamine receptor 2B
Uniprot ID
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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