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Anti-5HT2B Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT2B Receptor. Anti-5HT2B Receptor Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-5HT2B Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT2B Receptor. Anti-5HT2B Receptor Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Synonyms | Stomach fundus serotonin receptor, SR-2B, Serotonin receptor 2B, SEROTONIN 5HT2B RECEPTOR, NP75 protein, Htr2b, Htr 2b, 5-hydroxytryptamine receptor 2B, 5HT2F, 5HT2B_HUMAN, 5-HT-2B, 5-HT2B, 5HT(2B), 5 hydroxytryptamine(serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine(serotonin) receptor 2B, 5 hydroxytryptamine receptor 2B, 5 hydroxytryptamine 2B receptor, 5 HT2B, 5 HT(2B), 5 HT 2B receptor, 5 HT 2B |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (5HT2B Receptor) Polyclonal Antibody, Unconjugated (TMAB-02104) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Sample: Lane 1: Human HepG2 cell lysates Lane 2: Human SH-SY5Y cell lysates Lane 3: Human MCF-7 cell lysates Lane 4: Human HeLa cell lysates Primary: Anti-5HT2B Receptor (TMAB-02104) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 60 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]. |
| Immunogen | KLH conjugated synthetic peptide: human 5HT2B Receptor/SR-2B |
| Antigen Species | Human |
| Gene Name | HTR2B |
| Gene ID | |
| Protein Name | 5-hydroxytryptamine receptor 2B |
| Uniprot ID | |
| Function | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. |
| Molecular Weight | Theoretical: 54 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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