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Anti-FAM126A Polyclonal Antibody

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Catalog No. TMAB-05824

Anti-FAM126A Polyclonal Antibody is a Rabbit antibody targeting FAM126A. Anti-FAM126A Polyclonal Antibody can be used in WB.

Anti-FAM126A Polyclonal Antibody

Anti-FAM126A Polyclonal Antibody

😃Good
Catalog No. TMAB-05824
Anti-FAM126A Polyclonal Antibody is a Rabbit antibody targeting FAM126A. Anti-FAM126A Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FAM126A Polyclonal Antibody is a Rabbit antibody targeting FAM126A. Anti-FAM126A Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane. According to PubMed:10910037, it is mainly cytoplasmic while according to PubMed:16951682, it is a membrane protein.
Tissue SpecificityWidely expressed. Highest levels in heart, brain, placenta, spleen and testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the ∫-catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FAM126A
Antigen Species
Human
Gene Name
FAM126A
Gene ID
84668
Protein Name
Hyccin
Uniprot ID
Q9BYI3
Function
May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system.
Chemical Properties
Molecular WeightTheoretical: 58 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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