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Anti-STXBP1/Munc18-1 Polyclonal Antibody

Catalog No. TMAB-13253 Copy Product Info
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Anti-STXBP1/Munc18-1 Polyclonal Antibody is a Rabbit antibody targeting STXBP1/Munc18-1. Anti-STXBP1/Munc18-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-STXBP1/Munc18-1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-13253

Anti-STXBP1/Munc18-1 Polyclonal Antibody is a Rabbit antibody targeting STXBP1/Munc18-1. Anti-STXBP1/Munc18-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-STXBP1/Munc18-1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-STXBP1/Munc18-1 Polyclonal Antibody is a Rabbit antibody targeting STXBP1/Munc18-1. Anti-STXBP1/Munc18-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat spinal cord); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (STXBP1 Munc18-1) Polyclonal Antibody, Unconjugated (TMAB-13253) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane; Peripheral membrane protein.
Tissue SpecificityBrain and spinal cord. Highly enriched in axons.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Munc18
Antigen Species
Human
Gene Name
STXBP1
Gene ID
6812
Protein Name
Syntaxin-binding protein 1
Uniprot ID
P61764
Function
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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