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Anti-DENTT Polyclonal Antibody
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Catalog No. TMAB-05087
Anti-DENTT Polyclonal Antibody is a Rabbit antibody targeting DENTT. Anti-DENTT Polyclonal Antibody can be used in ICC/IF.
Anti-DENTT Polyclonal Antibody
Anti-DENTT Polyclonal Antibody
😃Good
Catalog No. TMAB-05087
Anti-DENTT Polyclonal Antibody is a Rabbit antibody targeting DENTT. Anti-DENTT Polyclonal Antibody can be used in ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DENTT Polyclonal Antibody is a Rabbit antibody targeting DENTT. Anti-DENTT Polyclonal Antibody can be used in ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | ICC/IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons. |
| Tissue Specificity | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CASK interacting nucleosome assembly protein (CINAP) modulates gene expression and its abundance in cultured neurons is regulated by synaptic activity. CINAP is widely expressed in different regions of adult mouse brain, including the cerebral cortex, hippocampus, striatum, hypothalamus, cerebellum, and two adult brain regions known to generate progenitor neurons. During early development, CINAP is also expressed in regions where neuronal progenitor cells are actively dividing, the ventricular and subventricular zones, suggesting that in addition to regulating gene expression in mature neurons CINAP may also play a role in dividing cells. |
| Immunogen | KLH conjugated synthetic peptide: human DENTT |
| Antigen Species | Human |
| Gene Name | TSPYL2 |
| Gene ID | |
| Protein Name | Testis-specific Y-encoded-like protein 2 |
| Uniprot ID | |
| Function | Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Molecular Weight | Theoretical: 76 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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