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Anti-TNNI3K Polyclonal Antibody
😃Good
Catalog No. TMAB-13654
Anti-TNNI3K Polyclonal Antibody is a Rabbit antibody targeting TNNI3K. Anti-TNNI3K Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TNNI3K Polyclonal Antibody
Anti-TNNI3K Polyclonal Antibody
😃Good
Catalog No. TMAB-13654
Anti-TNNI3K Polyclonal Antibody is a Rabbit antibody targeting TNNI3K. Anti-TNNI3K Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TNNI3K Polyclonal Antibody is a Rabbit antibody targeting TNNI3K. Anti-TNNI3K Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Expressed at lower levels in the cytoplasm. |
| Tissue Specificity | Highly expressed in both adult and fetal heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | TNNI3K, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart. Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response. TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, therefore protecting the myocardium from ischemic injury. Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases. There are four isoforms of TNNI3K that are produced as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human TNNI3K |
| Antigen Species | Human |
| Gene Name | TNNI3K |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase TNNI3K |
| Uniprot ID | |
| Function | May play a role in cardiac physiology. |
| Molecular Weight | Theoretical: 93 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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