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Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

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Catalog No. TMAB-11387

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-TPH2 (Ser19). Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

😃Good
Catalog No. TMAB-11387
Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-TPH2 (Ser19). Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-TPH2 (Ser19). Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Dog,Horse)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityBrain specific.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundPhenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and tryptophan hydroxylase 2 (TPH2) comprise a small family of monooxygenases that catalyze the rate-limiting step in the catabolism of aromatic L-amino acids and utilize tetrahydropterine as a cofactor. TPH2 is highly expressed in the central nervous system (CNS), mainly in the brain. TPH2 catalyzes the first step in the biosynthesis of serotonin in the CNS and melatonin in the pineal gland, and may be involved in the pathology of several neuropsychiatric disorders. Glucocorticoid-mediated reduction of TPH2 is associated with the etiology of mood disorders, specifically psychotic major depression, and TPH2 may be related to dysregulation of serotonin neurotransmission in the brain which commonly leads to suicidal behavior.
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human TPH2 around the phosphorylation site of Ser19
Antigen Species
Human
Gene Name
TPH2
Gene ID
121278
Protein Name
Tryptophan 5-hydroxylase 2
Uniprot ID
Q8IWU9
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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