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Anti-CD4 Polyclonal Antibody 3
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Catalog No. TMAB-03979
Anti-CD4 Polyclonal Antibody 3 is a Rabbit antibody targeting CD4. Anti-CD4 Polyclonal Antibody 3 can be used in WB.
Anti-CD4 Polyclonal Antibody 3
Anti-CD4 Polyclonal Antibody 3
Copy Product Info😃Good
Catalog No. TMAB-03979
Anti-CD4 Polyclonal Antibody 3 is a Rabbit antibody targeting CD4. Anti-CD4 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CD4 Polyclonal Antibody 3 is a Rabbit antibody targeting CD4. Anti-CD4 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Sheep,GuineaPig,MACFA) |
| Verified Activity | Sample: Spleen (Mouse) Lysate at 40 μg Lymph node (Mouse) Lysate at 40 μg Thymus (Mouse) Lysate at 40 μg Cerebrum (Mouse) Lysate at 40 μg Thymus (Rat) Lysate at 40 μg Molt-4 (Human) Cell Lysate at 30 μg HL60 (Human) Cell Lysate at 30 μg Jurkat (Human) Cell Lysate at 30 μg Raji (Human) Cell Lysate at 30 μg Primary: Anti-CD4 (TMAB-03979) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 53 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]. |
| Immunogen | KLH conjugated synthetic peptide: human CD4 |
| Antigen Species | Human |
| Gene Name | CD4 |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD4 |
| Uniprot ID | |
| Function | Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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