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Anti-RNF169 Polyclonal Antibody

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Catalog No. TMAB-12305

Anti-RNF169 Polyclonal Antibody is a Rabbit antibody targeting RNF169. Anti-RNF169 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-RNF169 Polyclonal Antibody

Anti-RNF169 Polyclonal Antibody

😃Good
Catalog No. TMAB-12305
Anti-RNF169 Polyclonal Antibody is a Rabbit antibody targeting RNF169. Anti-RNF169 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-RNF169 Polyclonal Antibody is a Rabbit antibody targeting RNF169. Anti-RNF169 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundRNF169 contains 1 RING type zinc finger. The exact functions of RNF169 remain unknown.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human RNF169
Antigen Species
Human
Gene Name
RNF169
Gene ID
Protein Name
E3 ubiquitin-protein ligase RNF169
Uniprot ID
Function
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
Chemical Properties
Molecular WeightTheoretical: 77 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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