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Anti-SISP1 Polyclonal Antibody
Catalog No. TMAB-12821 Copy Product Info
🥰Excellent
Anti-SISP1 Polyclonal Antibody is a Rabbit antibody targeting SISP1. Anti-SISP1 Polyclonal Antibody can be used in WB.
Anti-SISP1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-12821
Anti-SISP1 Polyclonal Antibody is a Rabbit antibody targeting SISP1. Anti-SISP1 Polyclonal Antibody can be used in WB.
Anti-SISP1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SISP1 Polyclonal Antibody is a Rabbit antibody targeting SISP1. Anti-SISP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with SISP1 polyclonal antibody, unconjugated (TMAB-12821) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. |
| Immunogen | KLH conjugated synthetic peptide: human SISP1/GI24 |
| Antigen Species | Human |
| Gene Name | VSIR |
| Gene ID | |
| Protein Name | V-type immunoglobulin domain-containing suppressor of T-cell activation |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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