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Anti-Neuroglycan C Polyclonal Antibody
😃Good
Catalog No. TMAB-09392
Anti-Neuroglycan C Polyclonal Antibody is a Rabbit antibody targeting Neuroglycan C. Anti-Neuroglycan C Polyclonal Antibody can be used in WB.
Anti-Neuroglycan C Polyclonal Antibody
Anti-Neuroglycan C Polyclonal Antibody
😃Good
Catalog No. TMAB-09392
Anti-Neuroglycan C Polyclonal Antibody is a Rabbit antibody targeting Neuroglycan C. Anti-Neuroglycan C Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Neuroglycan C Polyclonal Antibody is a Rabbit antibody targeting Neuroglycan C. Anti-Neuroglycan C Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reticulum and the Golgi (By similarity). Partially enriched in lipid rafts. |
| Tissue Specificity | Restricted to brain (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Neuroglycan C is a brain-specific chondroitin sulfate proteoglycan (CSPG) implicated in the proliferation of neural stem and progenitor cells. Neuro-glycan C is a single-pass membrane protein that can manifest as a part-time proteoglycan depending on the tissue expressing it. In its proteoglycan form, Neuroglycan C exhibits chondroitin sulfate glycans and functions as a receptor for midkine, a growth factor that binds heparin, to affect cytoskeletal changes. By means of ectodomain shedding, the ectodomain of Neuroglycan C is able to enhance neurite outgrowth from neurons. Neurite growth stimulation is affected by both an EGF-like and an acidic amino acid domain found on the shed ectodomain. Both domains instigate neurite growth, however, these domains exhibit differing functionality as to number of neurites produced and neuron types stimulated. |
| Immunogen | KLH conjugated synthetic peptide: human Neuroglycan C |
| Antigen Species | Human |
| Gene Name | CSPG5 |
| Gene ID | |
| Protein Name | Chondroitin sulfate proteoglycan 5 |
| Uniprot ID | |
| Function | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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