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Anti-DENND1B Polyclonal Antibody

Catalog No. TMAB-05081 Copy Product Info
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Anti-DENND1B Polyclonal Antibody is a Rabbit antibody targeting DENND1B. Anti-DENND1B Polyclonal Antibody can be used in WB.

Anti-DENND1B Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05081

Anti-DENND1B Polyclonal Antibody is a Rabbit antibody targeting DENND1B. Anti-DENND1B Polyclonal Antibody can be used in WB.

Anti-DENND1B Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DENND1B Polyclonal Antibody is a Rabbit antibody targeting DENND1B. Anti-DENND1B Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit)
Verified Activity
Sample: Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-DENND1B (TMAB-05081) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kD
Observed band size: 49 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytosol. Cytoplasmic vesicle, clathrin-coated vesicle.
Tissue SpecificityHighly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T-cells as compared with naive T-cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGuanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes. Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DENND1B
Antigen Species
Human
Gene Name
DENND1B
Gene ID
Protein Name
DENN domain-containing protein 1B
Uniprot ID
Function
Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactivates RAB35, then activates RAB35 for its subsequent function at endosomes.
Chemical Properties
Molecular WeightTheoretical: 48 kDa. Actual: 49 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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