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Anti-Neuroligin 1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-09397
Anti-Neuroligin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Neuroligin 1. Anti-Neuroligin 1 Polyclonal Antibody 2 can be used in WB.
Anti-Neuroligin 1 Polyclonal Antibody 2
Anti-Neuroligin 1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-09397
Anti-Neuroligin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Neuroligin 1. Anti-Neuroligin 1 Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Neuroligin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Neuroligin 1. Anti-Neuroligin 1 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Detected at dendritic spines. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1. |
| Tissue Specificity | Expressed in the blood vessel walls (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Neuroligin 1 is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. In addition, the neuroligin/beta-neurexin junction may be involved in the excitatory/inhibitory specification of CNS neuron synapses. A role for Neuroligin 1 is also suggested in autism. |
| Immunogen | KLH conjugated synthetic peptide: human Neuroligin 1 |
| Antigen Species | Human |
| Gene Name | NLGN1 |
| Gene ID | |
| Protein Name | Neuroligin-1 |
| Uniprot ID | |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. |
| Molecular Weight | Theoretical: 87 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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