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Anti-SIAH3 Polyclonal Antibody

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Catalog No. TMAB-12785

Anti-SIAH3 Polyclonal Antibody is a Rabbit antibody targeting SIAH3. Anti-SIAH3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SIAH3 Polyclonal Antibody

Anti-SIAH3 Polyclonal Antibody

😃Good
Catalog No. TMAB-12785
Anti-SIAH3 Polyclonal Antibody is a Rabbit antibody targeting SIAH3. Anti-SIAH3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SIAH3 Polyclonal Antibody is a Rabbit antibody targeting SIAH3. Anti-SIAH3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Dog,Horse,Rabbit,Sheep)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the SINA (seven in absentia) protein family are components of ubiquitin ligase complexes, which target proteins for proteasomal degradation. SIAH3 (seven in absentia homolog 3) is a 269 amino acid protein that belongs to the SINA family, contains one SIAH-type zinc finger and is encoded by a gene located on human chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SIAH3
Antigen Species
Human
Gene Name
SIAH3
Gene ID
283514
Protein Name
Seven in absentia homolog 3
Uniprot ID
Q8IW03
Chemical Properties
Molecular WeightTheoretical: 31 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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