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Anti-SPTBN2 Polyclonal Antibody

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Catalog No. TMAB-13143

Anti-SPTBN2 Polyclonal Antibody is a Rabbit antibody targeting SPTBN2. Anti-SPTBN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SPTBN2 Polyclonal Antibody

Anti-SPTBN2 Polyclonal Antibody

😃Good
Catalog No. TMAB-13143
Anti-SPTBN2 Polyclonal Antibody is a Rabbit antibody targeting SPTBN2. Anti-SPTBN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SPTBN2 Polyclonal Antibody is a Rabbit antibody targeting SPTBN2. Anti-SPTBN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Dog,Cow,Rabbit,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Tissue SpecificityHighly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSpectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin Alpha and spectrin Beta are present in erythrocytes, whereas spectrin Alpha II (also designated fodrin Alpha) and spectrin Beta I (also designated fodrin Beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin Beta III is highly homologous to both spectrin Beta I and spectrin Beta II. Western blot analysis shows that spectrin Beta III migrates at a higher molecular mass than predicted in the kidney. Spectrin Beta III is highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta. Specifically, spectrin Beta III constitutes a major component of the Golgi and vesicular membrane skeletons.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SPTBN2
Antigen Species
Human
Gene Name
SPTBN2
Gene ID
6712
Protein Name
Spectrin beta chain, non-erythrocytic 2
Uniprot ID
O15020
Function
Probably plays an important role in neuronal membrane skeleton.
Chemical Properties
Molecular WeightTheoretical: 271 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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