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Anti-WIPI2/Atg21 Polyclonal Antibody
😃Good
Catalog No. TMAB-14176
Anti-WIPI2/Atg21 Polyclonal Antibody is a Rabbit antibody targeting WIPI2/Atg21. Anti-WIPI2/Atg21 Polyclonal Antibody can be used in WB.
Anti-WIPI2/Atg21 Polyclonal Antibody
Anti-WIPI2/Atg21 Polyclonal Antibody
😃Good
Catalog No. TMAB-14176
Anti-WIPI2/Atg21 Polyclonal Antibody is a Rabbit antibody targeting WIPI2/Atg21. Anti-WIPI2/Atg21 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-WIPI2/Atg21 Polyclonal Antibody is a Rabbit antibody targeting WIPI2/Atg21. Anti-WIPI2/Atg21 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Chicken) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Preautophagosomal structure membrane. Enriched at preautophagosomal structure membranes in response to ptdIns3P. |
| Tissue Specificity | Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human WIPI2/Atg21 |
| Antigen Species | Human |
| Gene Name | WIPI2 |
| Gene ID | |
| Protein Name | WD repeat domain phosphoinositide-interacting protein 2 |
| Uniprot ID | |
| Function | Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P. |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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