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Anti-SHARPIN Polyclonal Antibody

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Catalog No. TMAB-12759

Anti-SHARPIN Polyclonal Antibody is a Rabbit antibody targeting SHARPIN. Anti-SHARPIN Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SHARPIN Polyclonal Antibody

Anti-SHARPIN Polyclonal Antibody

😃Good
Catalog No. TMAB-12759
Anti-SHARPIN Polyclonal Antibody is a Rabbit antibody targeting SHARPIN. Anti-SHARPIN Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SHARPIN Polyclonal Antibody is a Rabbit antibody targeting SHARPIN. Anti-SHARPIN Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Enriched at synaptic sites in mature neurons where it colocalizes with SHANK1.
Tissue SpecificityHighly expressed in skeletal muscle and placenta and at lower levels in brain, heart, colon without mucosa, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSHARPIN is a 387 amino acid protein that localizes to the cytoplasm and contains one RanBP2-type zinc finger. Expressed at high levels in placenta and skeletal muscle and present at lower levels in colon, brain, heart, liver, kidney, lung, thymus and small intestine, SHARPIN interacts with Shank 1 and is thought to play a role in the control of inflammatory responses and in the overall development of the immune system. SHARPIN exists as three alternatively spliced isoforms and shares 73% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding SHARPIN maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SHARPIN
Antigen Species
Human
Gene Name
SHARPIN
Gene ID
81858
Protein Name
Sharpin
Uniprot ID
Q9H0F6
Function
May have a role in normal immune development and control of inflammation.
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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