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Anti-NEU1/Neuraminidase Polyclonal Antibody

😃Good
Catalog No. TMAB-09370

Anti-NEU1/Neuraminidase Polyclonal Antibody is a Rabbit antibody targeting NEU1/Neuraminidase. Anti-NEU1/Neuraminidase Polyclonal Antibody can be used in WB.

Anti-NEU1/Neuraminidase Polyclonal Antibody

Anti-NEU1/Neuraminidase Polyclonal Antibody

😃Good
Catalog No. TMAB-09370
Anti-NEU1/Neuraminidase Polyclonal Antibody is a Rabbit antibody targeting NEU1/Neuraminidase. Anti-NEU1/Neuraminidase Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NEU1/Neuraminidase Polyclonal Antibody is a Rabbit antibody targeting NEU1/Neuraminidase. Anti-NEU1/Neuraminidase Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Rat,Cow)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles.
Tissue SpecificityHighly expressed in pancreas, followed by skeletal muscle, kidney, placenta, heart, lung and liver. Weakly expressed in brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NEU1/Neuraminidase
Antigen Species
Human
Gene Name
NEU1
Gene ID
Protein Name
Sialidase-1
Uniprot ID
Function
Catalyzes the removal of sialic acid (N-acetylneuramic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
Chemical Properties
Molecular WeightTheoretical: 45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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