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Anti-CD1E Polyclonal Antibody 2
😃Good
Catalog No. TMAB-03900
Anti-CD1E Polyclonal Antibody 2 is a Rabbit antibody targeting CD1E. Anti-CD1E Polyclonal Antibody 2 can be used in WB,FCM.
Anti-CD1E Polyclonal Antibody 2
Anti-CD1E Polyclonal Antibody 2
😃Good
Catalog No. TMAB-03900
Anti-CD1E Polyclonal Antibody 2 is a Rabbit antibody targeting CD1E. Anti-CD1E Polyclonal Antibody 2 can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD1E Polyclonal Antibody 2 is a Rabbit antibody targeting CD1E. Anti-CD1E Polyclonal Antibody 2 can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome lumen and Golgi apparatus membrane. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells. |
| Tissue Specificity | Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010] |
| Immunogen | KLH conjugated synthetic peptide: human CD1E |
| Antigen Species | Human |
| Gene Name | CD1E |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD1e, membrane-associated |
| Uniprot ID | |
| Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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