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Anti-MX1+MX2 Polyclonal Antibody

Catalog No. TMAB-09124 Copy Product Info
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Anti-MX1+MX2 Polyclonal Antibody is a Rabbit antibody targeting MX1+MX2. Anti-MX1+MX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-MX1+MX2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09124

Anti-MX1+MX2 Polyclonal Antibody is a Rabbit antibody targeting MX1+MX2. Anti-MX1+MX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-MX1+MX2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MX1+MX2 Polyclonal Antibody is a Rabbit antibody targeting MX1+MX2. Anti-MX1+MX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Sheep)
Verified Activity
Tissue/cell: human liver carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-MX1+MX2 Polyclonal Antibody, Unconjugated (TMAB-09124) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IFI78/MX1
Antigen Species
Human
Gene Name
MX2
Gene ID
Protein Name
Interferon-induced GTP-binding protein Mx2
Uniprot ID
Function
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus.
Chemical Properties
Molecular WeightTheoretical: 73/79 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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