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Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody
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Catalog No. TMAB-06466
Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody is a Rabbit antibody targeting N-octanoyl-Ghrelin 28 (Ser26). Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody
Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody
😃Good
Catalog No. TMAB-06466
Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody is a Rabbit antibody targeting N-octanoyl-Ghrelin 28 (Ser26). Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody is a Rabbit antibody targeting N-octanoyl-Ghrelin 28 (Ser26). Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014] |
| Immunogen | KLH conjugated synthesised n-octanoyl-peptide: human Ghrelin 28 around the n-octanoyl site of Ser26) |
| Antigen Species | Human |
| Gene Name | GHRL |
| Gene ID | |
| Protein Name | Appetite-regulating hormone |
| Uniprot ID | |
| Function | Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. |
| Molecular Weight | Theoretical: 3/12 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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