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Anti-GBP5 Polyclonal Antibody
Catalog No. TMAB-06367 Copy Product Info
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Anti-GBP5 Polyclonal Antibody is a Rabbit antibody targeting GBP5. Anti-GBP5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GBP5 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06367
Anti-GBP5 Polyclonal Antibody is a Rabbit antibody targeting GBP5. Anti-GBP5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GBP5 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GBP5 Polyclonal Antibody is a Rabbit antibody targeting GBP5. Anti-GBP5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GBP5) Polyclonal Antibody, Unconjugated (TMAB-06367) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Membrane; Lipid-anchor. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | GBP5 is a 586 amino acid protein that localizes to the cytoplasmic side of the cell membrane. Belonging to the interferon (IFN)-inducible guanylate-binding protein (GBP) family, GBP5 may be involved in the inflammatory response or with cell proliferation and is suggested to have possible cancer-related functions. The gene encoding GBP5 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Immunogen | KLH conjugated synthetic peptide: human GBP5/Guanylate binding protein 5 |
| Antigen Species | Human |
| Gene Name | GBP5 |
| Gene ID | |
| Protein Name | Guanylate-binding protein 5 |
| Uniprot ID | |
| Function | Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. |
| Molecular Weight | Theoretical: 66 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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