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Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody

Catalog No. TMAB-10592 Copy Product Info
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Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-10592

Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-delta 1 Catenin
(Tyr280) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (p-delta 1 Catenin (Tyr280)) Polyclonal Antibody, Unconjugated (TMAB-10592) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Tissue SpecificityExpressed in vascular endothelium.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundBinds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human delta 1 Catenin around the phosphorylation site of Tyr280
Antigen Species
Human
Gene Name
CTNND1
Gene ID
Protein Name
Catenin delta-1
Uniprot ID
Function
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Chemical Properties
Molecular WeightTheoretical: 106 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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