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Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody
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Catalog No. TMAB-10592
Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody
Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-10592
Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-delta 1 Catenin (Tyr280). Anti-Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (p-delta 1 Catenin (Tyr280)) Polyclonal Antibody, Unconjugated (TMAB-10592) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm. |
| Tissue Specificity | Expressed in vascular endothelium. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human delta 1 Catenin around the phosphorylation site of Tyr280 |
| Antigen Species | Human |
| Gene Name | CTNND1 |
| Gene ID | |
| Protein Name | Catenin delta-1 |
| Uniprot ID | |
| Function | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. |
| Molecular Weight | Theoretical: 106 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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