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Anti-PACAP receptor Polyclonal Antibody

Catalog No. TMAB-09914 Copy Product Info
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Anti-PACAP receptor Polyclonal Antibody is a Rabbit antibody targeting PACAP receptor. Anti-PACAP receptor Polyclonal Antibody can be used in WB.

Anti-PACAP receptor Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09914

Anti-PACAP receptor Polyclonal Antibody is a Rabbit antibody targeting PACAP receptor. Anti-PACAP receptor Polyclonal Antibody can be used in WB.

Anti-PACAP receptor Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PACAP receptor Polyclonal Antibody is a Rabbit antibody targeting PACAP receptor. Anti-PACAP receptor Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Rat Placenta tissue lysates
Lane 3: Human HeLa cell lysates
Lane 4: Human SH-SY5Y cell lysates
Lane 5: Human U87MG cell lysates
Primary: Anti-PACAP receptor (TMAB-09914) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kDa
Observed band size: 53, 60 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityMost abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundPituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the vasoactive intestinal polypeptide/glucagon/ secretin family. It is widely distributed in the body, and a variety of biological actions have been reported. Recent studies have shown that there is a family of PACAP receptors (PACAPRs), and two members of this family have been identified. This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). Belongs to the G-protein coupled receptor 2 family.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PACAP receptor
Antigen Species
Human
Gene Name
ADCYAP1R1
Gene ID
Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
Uniprot ID
Function
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
Chemical Properties
Molecular WeightTheoretical: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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