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Anti-Cyclin A1 Polyclonal Antibody 2

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Catalog No. TMAB-04820

Anti-Cyclin A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Cyclin A1. Anti-Cyclin A1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-Cyclin A1 Polyclonal Antibody 2

Anti-Cyclin A1 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-04820
Anti-Cyclin A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Cyclin A1. Anti-Cyclin A1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Cyclin A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Cyclin A1. Anti-Cyclin A1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A1 is expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. It binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Cyclin A1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cyclin A1
Antigen Species
Human
Gene Name
CCNA1
Gene ID
8900
Protein Name
Cyclin-A1
Uniprot ID
P78396
Function
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
Chemical Properties
Molecular WeightTheoretical: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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