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Anti-F2 Monoclonal Antibody-Biotin is a biotin-conjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $373 | 12 days | |
50 μg | $448 | 12 days | |
100 μg | $627 | 12 days |
Description | Anti-F2 Monoclonal Antibody-Biotin is a biotin-conjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody-Biotin can be used in ELISA, FACS. |
Alias | Prothrombin, Coagulation factor II |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of F2 overexpressed 448F cells with TMAZ-0378B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of F2 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in PBS. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Thrombin triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells (PubMed:30568593, PubMed:9780208) |
Conjucates | Biotin |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | F2 |
Antigen Species | Human |
Gene ID | 2147 |
Uniprot ID | |
Biology Area | Drug Target |
Molecular Weight | 150 kDa |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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