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Anti-NCR1 Polyclonal Antibody 3
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Catalog No. TMAB-09287
Anti-NCR1 Polyclonal Antibody 3 is a Rabbit antibody targeting NCR1. Anti-NCR1 Polyclonal Antibody 3 can be used in WB.
Anti-NCR1 Polyclonal Antibody 3
Anti-NCR1 Polyclonal Antibody 3
Copy Product Info😃Good
Catalog No. TMAB-09287
Anti-NCR1 Polyclonal Antibody 3 is a Rabbit antibody targeting NCR1. Anti-NCR1 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-NCR1 Polyclonal Antibody 3 is a Rabbit antibody targeting NCR1. Anti-NCR1 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep) |
| Verified Activity | 1. Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Rat Lymph node tissue lysates Lane 4: Human HL-60 cell lysates Primary: Anti-NCR1 (TMAB-09287) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 48 kDa 2. Sample: Kidney (Mouse) Lysate at 40 μg Spleen (Mouse) Lysate at 40 μg Lymph node (Mouse) Lysate at 40 μg A431 (Human) Cell Lysate at 30 μg Raji (Human) Cell Lysate at 30 μg Primary: Anti-NCR1 (TMAB-09287) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 46 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |
| Immunogen | KLH conjugated synthetic peptide: human CD335 |
| Antigen Species | Human |
| Gene Name | NCR1 |
| Gene ID | |
| Protein Name | Natural cytotoxicity triggering receptor 1 |
| Uniprot ID | |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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