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Anti-IL-10RA Polyclonal Antibody
Catalog No. TMAB-07594 Copy Product Info
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Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB.
Anti-IL-10RA Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07594
Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB.
Anti-IL-10RA Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow) |
| Verified Activity | Sample: Lane 1: Human K562 cell Lysates Lane 2: Human THP-1 cell Lysates Lane 3: Human Jurkat cell Lysates Primary: Anti-IL-10RA (TMAB-07594) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kDa Observed band size: 55 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human IL-10RA |
| Antigen Species | Human |
| Gene Name | IL10RA |
| Gene ID | |
| Protein Name | Interleukin-10 receptor subunit alpha |
| Uniprot ID | |
| Function | Receptor for IL10; binds IL10 with a high affinity. |
| Molecular Weight | Theoretical: 60 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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