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Anti-IL-10RA Polyclonal Antibody

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Catalog No. TMAB-07594

Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB.

Anti-IL-10RA Polyclonal Antibody

Anti-IL-10RA Polyclonal Antibody

😃Good
Catalog No. TMAB-07594
Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Pig,Cow)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificitySpleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IL-10RA
Antigen Species
Human
Gene Name
IL10RA
Gene ID
Protein Name
Interleukin-10 receptor subunit alpha
Uniprot ID
Function
Receptor for IL10; binds IL10 with a high affinity.
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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