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Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody

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Catalog No. TMAB-06602

Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody is a Rabbit antibody targeting GNAI2/G protein alpha inhibitor 1. Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody

Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-06602
Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody is a Rabbit antibody targeting GNAI2/G protein alpha inhibitor 1. Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody is a Rabbit antibody targeting GNAI2/G protein alpha inhibitor 1. Anti-GNAI2/G protein alpha inhibitor 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GNAI2 G protein alpha inhibitor 1) Polyclonal Antibody, Unconjugated (TMAB-06602) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm, cytoskeleton, centrosome. Cell membrane. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe G protein family of signal transducers includes 5 heterotrimers, which are most clearly distinguished by their different alpha chains; they have virtually identical beta chains and similar gamma chains. G protein alpha inhibitor chains 1 and 2 are subunits of the G(i) G protein, whose role is in inhibiting adenylate cyclase activity in response to bound GTP.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human G Protein alpha Inhibitor 1
Antigen Species
Human
Gene Name
GNAI2
Gene ID
Protein Name
Guanine nucleotide-binding protein G(i) subunit alpha-2
Uniprot ID
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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