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Anti-HGFA Inhibitor 2 Polyclonal Antibody
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Catalog No. TMAB-07012
Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM.
Anti-HGFA Inhibitor 2 Polyclonal Antibody
Anti-HGFA Inhibitor 2 Polyclonal Antibody
😃Good
Catalog No. TMAB-07012
Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,GuineaPig) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Tissue damage, such as hepatic and renal injury, initiates hepatocyte growth factor activator (HGFAC)-mediated limited proteolytic activation of the inactive single-chain precursor form of HGF. Initially, HGFAC is produced as a precursor protein, which is activated by limited proteolysis and is neutralized by specific inhibitors known as HGF activator inhibitors, designated HAIs. HAIs belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various human tissues, such as adult placenta, kidney, pancreas, prostate and small intestine, and fetal kidney and lung. It translates into a 478 amino acid protein. The human HAI-2 gene maps to chromosome 19q13.1 and encodes a 252 amino acid protein, also designated human placental bikunin or kop (Kunitz domain containing protein over-expressed in pancreatic cancer). HAI-1 and HAI-2 are produced in membrane-associated forms, which are secreted as active, proteolytically truncated proteins. |
| Immunogen | KLH conjugated synthetic peptide: human SPINT2 |
| Antigen Species | Human |
| Gene Name | SPINT2 |
| Gene ID | |
| Protein Name | Kunitz-type protease inhibitor 2 |
| Uniprot ID | |
| Function | Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa. |
| Molecular Weight | Theoretical: 28 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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