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Anti-HGFA Inhibitor 2 Polyclonal Antibody
Catalog No. TMAB-07012 Copy Product Info
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Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM.
Anti-HGFA Inhibitor 2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07012
Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM.
Anti-HGFA Inhibitor 2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-HGFA Inhibitor 2 Polyclonal Antibody is a Rabbit antibody targeting HGFA Inhibitor 2. Anti-HGFA Inhibitor 2 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,GuineaPig) |
| Verified Activity | Blank control (blue): Mouse thymus Cells (fixed with 2% paraformaldehyde (10 min)). Primary Antibody: Rabbit Anti-HGFA antibody (TMAB-07012), Dilution: 1 μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG (orange), used under the same conditions); Secondary Antibody: Goat anti-rabbit IgG-PE (white blue), Dilution: 1: 200 in 1 X PBS containing 0.5% BSA. |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Tissue damage, such as hepatic and renal injury, initiates hepatocyte growth factor activator (HGFAC)-mediated limited proteolytic activation of the inactive single-chain precursor form of HGF. Initially, HGFAC is produced as a precursor protein, which is activated by limited proteolysis and is neutralized by specific inhibitors known as HGF activator inhibitors, designated HAIs. HAIs belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various human tissues, such as adult placenta, kidney, pancreas, prostate and small intestine, and fetal kidney and lung. It translates into a 478 amino acid protein. The human HAI-2 gene maps to chromosome 19q13.1 and encodes a 252 amino acid protein, also designated human placental bikunin or kop (Kunitz domain containing protein over-expressed in pancreatic cancer). HAI-1 and HAI-2 are produced in membrane-associated forms, which are secreted as active, proteolytically truncated proteins. |
| Immunogen | KLH conjugated synthetic peptide: human SPINT2 |
| Antigen Species | Human |
| Gene Name | SPINT2 |
| Gene ID | |
| Protein Name | Kunitz-type protease inhibitor 2 |
| Uniprot ID | |
| Function | Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa. |
| Molecular Weight | Theoretical: 28 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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