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Anti-CENPC1 Polyclonal Antibody
Catalog No. TMAB-04224 Copy Product Info
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Anti-CENPC1 Polyclonal Antibody is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Polyclonal Antibody can be used in WB.
Anti-CENPC1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04224
Anti-CENPC1 Polyclonal Antibody is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Polyclonal Antibody can be used in WB.
Anti-CENPC1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CENPC1 Polyclonal Antibody is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Horse,Rabbit) |
| Verified Activity | Sample: Lane 1: Human HeLa cell lysates Lane 2: Human Jurkat cell lysates Lane 3: Human K562 cell lysates Lane 4: Human HepG2 cell lysates Lane 5: Human A431 cell lysates Primary: Anti-CENPC1 (TMAB-04224) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 107 kDa Observed band size: 105 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. |
| Immunogen | KLH conjugated synthetic peptide: human CENPC1 |
| Antigen Species | Human |
| Gene Name | CENPC |
| Gene ID | |
| Protein Name | Centromere protein C |
| Uniprot ID | |
| Function | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. |
| Molecular Weight | Theoretical: 107 kDa. Actual: 105 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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