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Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody
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Catalog No. TMAB-11144
Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKA alpha+beta (Thr198). Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody
Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody
😃Good
Catalog No. TMAB-11144
Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKA alpha+beta (Thr198). Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKA alpha+beta (Thr198). Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. Nucleus. Note=Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm. |
| Tissue Specificity | Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human PRKACB around the phosphorylation site of Thr198 |
| Antigen Species | Human |
| Gene Name | PRKACB |
| Gene ID | |
| Protein Name | cAMP-dependent protein kinase catalytic subunit beta |
| Function | Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
| Molecular Weight | Theoretical: 40 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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