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Anti-CK10 Polyclonal Antibody

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Catalog No. TMAB-04381

Anti-CK10 Polyclonal Antibody is a Rabbit antibody targeting CK10. Anti-CK10 Polyclonal Antibody can be used in ICC/IF,FCM.

Anti-CK10 Polyclonal Antibody

Anti-CK10 Polyclonal Antibody

😃Good
Catalog No. TMAB-04381
Anti-CK10 Polyclonal Antibody is a Rabbit antibody targeting CK10. Anti-CK10 Polyclonal Antibody can be used in ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CK10 Polyclonal Antibody is a Rabbit antibody targeting CK10. Anti-CK10 Polyclonal Antibody can be used in ICC/IF,FCM.
Ig Type
IgG
Reactivity
Human
Application
ICC/IF
FCM
Recommended Dose
ICC/IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificitySeen in all suprabasal cell layers including stratum corneum.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CK10
Antigen Species
Human
Gene Name
KRT10
Gene ID
3858
Protein Name
Keratin, type I cytoskeletal 10
Uniprot ID
P13645
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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