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Anti-FGF3 Polyclonal Antibody
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Catalog No. TMAB-05992 Copy Product Info
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Anti-FGF3 Polyclonal Antibody is a Rabbit antibody targeting FGF3. Anti-FGF3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-FGF3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $222 | 7-10 days | 7-10 days | |
| 100 µL | $372 | 7-10 days | 7-10 days | |
| 200 µL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-FGF3 Polyclonal Antibody is a Rabbit antibody targeting FGF3. Anti-FGF3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (FGF3) Polyclonal Antibody, Unconjugated (TMAB-05992) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. |
| Immunogen | KLH conjugated synthetic peptide: human FGF3 |
| Antigen Species | Human |
| Gene Name | FGF3 |
| Gene ID | |
| Protein Name | Fibroblast growth factor 3 |
| Uniprot ID | |
| Function | Fibroblast growth factors (FGFs) can stimulate the proliferation of mesenchymal, epithelial and neuroectodermal cells. FGF3 belongs to the heparin binding growth factors family. Members of the family include Acidic FGF (also known as aFGF or FGF 1), basic FGF (bFGF or FGF 2), FGF 3 (also known as Int2) and FGF 4 (also known as hst or Kaposi FGF). FGF 4 was first revealed to be an oncoprotein in Kaposi's sarcoma cells. Other family members include FGF 5, FGF 6, FGF 7 (keratinocyte growth factor, KGF), FGF 8 (AIGF), FGF 9 (GAF) and FGF 10. FGF3 is activated by proviral insertion of mouse mammary tumor virus (MMTV). FGF3 is responsible for most of breast malignancies. |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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