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Anti-VMAT2 Polyclonal Antibody

Catalog No. TMAB-14122 Copy Product Info
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Anti-VMAT2 Polyclonal Antibody is a Rabbit antibody targeting VMAT2. Anti-VMAT2 Polyclonal Antibody can be used in WB.

Anti-VMAT2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-14122

Anti-VMAT2 Polyclonal Antibody is a Rabbit antibody targeting VMAT2. Anti-VMAT2 Polyclonal Antibody can be used in WB.

Anti-VMAT2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VMAT2 Polyclonal Antibody is a Rabbit antibody targeting VMAT2. Anti-VMAT2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse)
Verified Activity
Sample:
Lane 1: Mouse Adrenal gland tissue lysates
Lane 2: Mouse Cerebrum tissue lysates
Lane 3: Mouse Liver tissue lysates
Lane 4: Rat Cerebrum tissue lysates
Lane 5: Rat Stomach tissue lysates
Primary: Anti-VMAT2 (TMAB-14122) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kDa
Observed band size: 55 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic vesicle membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNeurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human VMAT2
Antigen Species
Human
Gene Name
SLC18A2
Gene ID
Protein Name
Synaptic vesicular amine transporter
Uniprot ID
Function
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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