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Anti-GPR24 Polyclonal Antibody
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Catalog No. TMAB-06705
Anti-GPR24 Polyclonal Antibody is a Rabbit antibody targeting GPR24. Anti-GPR24 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GPR24 Polyclonal Antibody
Anti-GPR24 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-06705
Anti-GPR24 Polyclonal Antibody is a Rabbit antibody targeting GPR24. Anti-GPR24 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GPR24 Polyclonal Antibody is a Rabbit antibody targeting GPR24. Anti-GPR24 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Cow,Horse) |
| Verified Activity | Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-GPR24 Polyclonal Antibody, Unconjugated (TMAB-06705) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell Membrane; multi-pass membrane protein |
| Tissue Specificity | Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin. |
| Immunogen | KLH conjugated synthetic peptide: human MCHR/GPR24 |
| Antigen Species | Human |
| Gene Name | MCHR1 |
| Gene ID | |
| Protein Name | Melanin-concentrating hormone receptor 1 |
| Uniprot ID | |
| Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. |
| Molecular Weight | Theoretical: 46 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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