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Anti-LGI3 Polyclonal Antibody

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Catalog No. TMAB-08291

Anti-LGI3 Polyclonal Antibody is a Rabbit antibody targeting LGI3. Anti-LGI3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-LGI3 Polyclonal Antibody

Anti-LGI3 Polyclonal Antibody

😃Good
Catalog No. TMAB-08291
Anti-LGI3 Polyclonal Antibody is a Rabbit antibody targeting LGI3. Anti-LGI3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LGI3 Polyclonal Antibody is a Rabbit antibody targeting LGI3. Anti-LGI3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Horse,Sheep)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted (Potential). Cytoplasmic vesicle, secretory vesicle, synaptic vesicle (By similarity). Cell junction, synapse, synaptosome (By similarity). Note=Found in the synaptosomal membrane fraction
Tissue SpecificityWidely expressed, with highest levels in brain and lung.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LGI3
Antigen Species
Human
Gene Name
LGI3
Gene ID
203190
Protein Name
Leucine-rich repeat LGI family member 3
Uniprot ID
Q8N145
Function
May participate in the regulation of neuronal exocytosis.
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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