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Anti-DENND2C Polyclonal Antibody
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Catalog No. TMAB-05082
Anti-DENND2C Polyclonal Antibody is a Rabbit antibody targeting DENND2C. Anti-DENND2C Polyclonal Antibody can be used in WB.
Anti-DENND2C Polyclonal Antibody
Anti-DENND2C Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-05082
Anti-DENND2C Polyclonal Antibody is a Rabbit antibody targeting DENND2C. Anti-DENND2C Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-DENND2C Polyclonal Antibody is a Rabbit antibody targeting DENND2C. Anti-DENND2C Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: 293T Cell (Human) Lysate at 30 μg Hela Cell (Human) Lysate at 30 μg Primary: Anti-DENND2C (TMAB-05082) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 107 kD Observed band size: 107 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome. |
| Immunogen | KLH conjugated synthetic peptide: human DENND2C |
| Antigen Species | Human |
| Gene Name | DENND2C |
| Gene ID | |
| Protein Name | DENN domain-containing protein 2C |
| Uniprot ID | |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. |
| Molecular Weight | Theoretical: 107 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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