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Anti-FCGRT Polyclonal Antibody
😃Good
Catalog No. TMAB-05947
Anti-FCGRT Polyclonal Antibody is a Rabbit antibody targeting FCGRT. Anti-FCGRT Polyclonal Antibody can be used in WB,FCM.
Anti-FCGRT Polyclonal Antibody
Anti-FCGRT Polyclonal Antibody
😃Good
Catalog No. TMAB-05947
Anti-FCGRT Polyclonal Antibody is a Rabbit antibody targeting FCGRT. Anti-FCGRT Polyclonal Antibody can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FCGRT Polyclonal Antibody is a Rabbit antibody targeting FCGRT. Anti-FCGRT Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 3μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn å chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins. |
| Immunogen | KLH conjugated synthetic peptide: human FCGRT/FcRn |
| Antigen Species | Human |
| Gene Name | FCGRT |
| Gene ID | |
| Protein Name | IgG receptor FcRn large subunit p51 |
| Uniprot ID | |
| Function | Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. |
| Molecular Weight | Theoretical: 37 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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