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Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody
Catalog No. TMAB-10614 Copy Product Info
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Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EDG1 (Thr236). Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody can be used in WB.
Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-10614
Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EDG1 (Thr236). Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody can be used in WB.
Anti-Phospho-EDG1
(Thr236) Polyclonal Antibody
(Thr236) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EDG1 (Thr236). Anti-Phospho-EDG1 (Thr236) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Rabbit) |
| Verified Activity | 1. Sample: Thymus (Mouse) Lysate at 40 μg Primary: Anti-phospho-EDG1 (Thr236) (TMAB-10614) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD 2. Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Rat Cerebellum tissue lysates Primary: Anti-phospho-EDG1 (Thr236) (TMAB-10614) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kDa Observed band size: 45 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphingosine-1-phosphate receptor subfamily comprising five members (S1PR1-5). S1PR1 was originally identified as an abundant transcript in endothelial cells and it has an important role in regulating endothelial cell cytoskeletal structure, migration, capillary-like network formation and vascular maturation. In addition, S1PR1 signaling is important in the regulation of lymphocyte maturation, migration and trafficking. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human EDG1 around the phosphorylation site of Thr236 |
| Antigen Species | Human |
| Gene Name | S1PR1 |
| Gene ID | |
| Protein Name | Sphingosine 1-phosphate receptor 1 |
| Uniprot ID | |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins. |
| Molecular Weight | Theoretical: 43 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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