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Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2
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Catalog No. TMAB-10456
Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Cdc25B (Ser149). Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2
Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-10456
Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Cdc25B (Ser149). Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Cdc25B (Ser149). Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human Cdc25B around the phosphorylation site of Ser149 |
| Antigen Species | Human |
| Gene Name | CDC25B |
| Gene ID | |
| Protein Name | M-phase inducer phosphatase 2 |
| Uniprot ID | |
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. |
| Molecular Weight | Theoretical: 65 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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