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Anti-Endothelin B Receptor Polyclonal Antibody
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Catalog No. TMAB-05572
Anti-Endothelin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Polyclonal Antibody can be used in WB.
Anti-Endothelin B Receptor Polyclonal Antibody
Anti-Endothelin B Receptor Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-05572
Anti-Endothelin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Endothelin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: Lane1: Heart (Rat) Lysate at 40 μg Lane2: Heart (Mouse) Lysate at 40 μg Primary: Anti-Endothelin B Receptor(TMAB-05572) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 50 kD 2. Sample: Lane 1: Embryo (Mouse) Tissue Lysate at 40 μg Lane 2: Lung (Mouse) TissueLysate at 40 μg Lane 3: Cerebrum (Mouse) Tissue Lysate at 40 μg Lane 4: Cerebrum (Rat) Tissue Lysate at 40 μg Lane 5: A431 (Human) Cell Lysate at 30 μg Lane 6: BV-2 (Mouse) Cell Lysate at 30 μg Lane 7: SH-SY5Y (Human) Cell Lysate at 30 μg Primary: Anti-Endothelin B Receptor (TMAB-05572) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 50 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding - suggesting that these two variants are functionally distinct. |
| Immunogen | KLH conjugated synthetic peptide: human Endothelin B Receptor |
| Antigen Species | Human |
| Gene Name | EDNRB |
| Gene ID | |
| Protein Name | Endothelin receptor type B |
| Uniprot ID | |
| Function | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Molecular Weight | Theoretical: 47 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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