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Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2

Catalog No. TMAB-10723 Copy Product Info
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Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-G3BP1 (Ser232). Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 can be used in WB.

Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-10723

Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-G3BP1 (Ser232). Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 can be used in WB.

Anti-Phospho-G3BP1
(Ser232) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-G3BP1 (Ser232). Anti-Phospho-G3BP1 (Ser232) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Pig,Cow,Rabbit)
Verified Activity
Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human HeLa cell lysates
Primary: Anti-phospho-G3BP1 (Ser232) (TMAB-10723) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52-60 kDa
Observed band size: 62 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm, cytosol. Cell membrane. Nucleus. Note=Cytoplasmic in proliferating cells, can be recruited to the plasma membrane in exponentially growing cells. Cytosolic and partially nuclear in resting cells. Recruited to stress granules (SGs) upon either arsenite or high temperature treatment. Recruitment to SGs is influenced by HRAS.
Tissue SpecificityUbiquitous.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human G3BP1 around the phosphorylation site of Ser232
Antigen Species
Human
Gene Name
G3BP1
Gene ID
Protein Name
Ras GTPase-activating protein-binding protein 1
Uniprot ID
Function
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Chemical Properties
Molecular WeightTheoretical: 52-60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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