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Antiviral agent 34

Name: Antiviral agent 34
Brand: TargetMol
SKU: T77632
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77632Cas No. 945152-88-5

Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of influenza viruses by modulating RNA polymerase.Antiviral agent 34 is used in the study of viral infections.

Antiviral agent 34

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Purity: 99.51%

Catalog No. T77632Cas No. 945152-88-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$483	In Stock	In Stock
10 mg	$692	In Stock	In Stock
25 mg	$1,080	In Stock	In Stock
50 mg	$1,490	In Stock	In Stock
100 mg	$1,970	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.51%

Appearance:Solid

Color:White

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of influenza viruses by modulating RNA polymerase.Antiviral agent 34 is used in the study of viral infections.
Targets&IC50	influenza A (EC50):0.8 nM, influenza B:0.8 nM (EC50)
In vitro	In MDCK cells, Antiviral agent 34 (0-470 nM; 24 hours) exhibited low toxicity to MDCK cells[1].
In vivo	In BALB/c mice, Antiviral agent 34 (1 g/kg/d, administered orally for 14 days) was well tolerated at a dose of 1 g/kg with low acute toxicity. It provided approximately 50% protection in mice infected with a lethal dose of H1N1[1].

Chemical Properties

Molecular Weight	487.66
Formula	C₂₉H₃₃N₃O₂S
Cas No.	945152-88-5
Smiles	O=C(NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CC=C(C=C3)C(C)(C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (205.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0506 mL	10.2530 mL	20.5061 mL	102.5305 mL
5 mM	0.4101 mL	2.0506 mL	4.1012 mL	20.5061 mL
10 mM	0.2051 mL	1.0253 mL	2.0506 mL	10.2530 mL
20 mM	0.1025 mL	0.5127 mL	1.0253 mL	5.1265 mL
50 mM	0.0410 mL	0.2051 mL	0.4101 mL	2.0506 mL
100 mM	0.0205 mL	0.1025 mL	0.2051 mL	1.0253 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc