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Anti-FMN1 Polyclonal Antibody 2

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Catalog No. TMAB-06084

Anti-FMN1 Polyclonal Antibody 2 is a Rabbit antibody targeting FMN1. Anti-FMN1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-FMN1 Polyclonal Antibody 2

Anti-FMN1 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-06084
Anti-FMN1 Polyclonal Antibody 2 is a Rabbit antibody targeting FMN1. Anti-FMN1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FMN1 Polyclonal Antibody 2 is a Rabbit antibody targeting FMN1. Anti-FMN1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Dog,Cow,Sheep)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Cell junction, adherens junction; Peripheral membrane protein; Cytoplasmic side.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FMN1/Formin 1
Antigen Species
Human
Gene Name
FMN1
Gene ID
Protein Name
Formin-1
Uniprot ID
Function
FMN1 plays a role in the formation of adherens junction and the polymerization of linear actin cables. Interacts with alpha-catenin and may interact with tubulin.
Chemical Properties
Molecular WeightTheoretical: 157 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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