Anti-RNF12 Polyclonal Antibody is a Rabbit antibody targeting RNF12. Anti-RNF12 Polyclonal Antibody can be used in WB.

IgG

Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)

1. Sample: placenta (Mouse) Lysate at 40 μg
Primary: Anti-RNF12 (TMAB-12284) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kD
Observed band size: 69 kD
2. Sample: U937 (Human) Cell Lysate at 30 μg
Primary: Anti-RNF12 (TMAB-12284) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kD
Observed band size: 67 kD

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human RNF12

Human

RLIM

E3 ubiquitin-protein ligase RLIM

E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.