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Anti-FAT Polyclonal Antibody

Catalog No. TMAB-05906 Copy Product Info
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Anti-FAT Polyclonal Antibody is a Rabbit antibody targeting FAT. Anti-FAT Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FAT Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05906

Anti-FAT Polyclonal Antibody is a Rabbit antibody targeting FAT. Anti-FAT Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FAT Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FAT Polyclonal Antibody is a Rabbit antibody targeting FAT. Anti-FAT Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (FAT) Polyclonal Antibody, Unconjugated (TMAB-05906) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Nucleus Cytoplasm, perinuclear region.
Tissue SpecificityExpressed in many epithelial and some endothelial and smooth muscle cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FAT/CDHF7
Antigen Species
Human
Gene Name
FAT1
Gene ID
Protein Name
Protocadherin Fat 1
Function
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
Chemical Properties
Molecular WeightTheoretical: 506 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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