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Anti-EPR1 Polyclonal Antibody

Catalog No. TMAB-05634 Copy Product Info
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Anti-EPR1 Polyclonal Antibody is a Rabbit antibody targeting EPR1. Anti-EPR1 Polyclonal Antibody can be used in WB.

Anti-EPR1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05634

Anti-EPR1 Polyclonal Antibody is a Rabbit antibody targeting EPR1. Anti-EPR1 Polyclonal Antibody can be used in WB.

Anti-EPR1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EPR1 Polyclonal Antibody is a Rabbit antibody targeting EPR1. Anti-EPR1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
JurkaT (Human) Cell Lysate at 30 μg
293T (Human) Cell Lysate at 30 μg
Primary: Anti-EPR1 (TMAB-05634) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 35 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human EPR1
Antigen Species
Human
Gene Name
EPR-1
Gene ID
Protein Name
Effector cell protease receptor 1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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