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Anti-C1r Polyclonal Antibody

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Catalog No. TMAB-03366 Copy Product Info
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Anti-C1r Polyclonal Antibody is a Rabbit antibody targeting C1r. Anti-C1r Polyclonal Antibody can be used in WB.
Anti-C1r Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-C1r Polyclonal Antibody is a Rabbit antibody targeting C1r. Anti-C1r Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the classical pathways of the serum complement system. C1 consists of a calcium dependent trimolecular complex of C1r, C1s and C1q in a 2:2:1 ratio. C1r is a dimer formed of two identical chains that are activated by cleavage into two chains, A and B.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Complement C1r subcomponent heavy chain
Antigen Species
Human
Gene Name
C1R
Gene ID
Protein Name
Complement C1r subcomponent
Uniprot ID
Function
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Chemical Properties
Molecular WeightTheoretical: 78 kDa. Actual: 78 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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