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Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody
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Catalog No. TMAB-02605
Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody is a Rabbit antibody targeting ANT1+ANT2+ANT3+ANT4. Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody
Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-02605
Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody is a Rabbit antibody targeting ANT1+ANT2+ANT3+ANT4. Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody is a Rabbit antibody targeting ANT1+ANT2+ANT3+ANT4. Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Horse,Rabbit) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ANT1+ANT2+ANT3+ANT4) Polyclonal Antibody, Unconjugated (TMAB-02605) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Sample: Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-ANT1+ANT2+ANT3+ANT4 (TMAB-02605) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kD Observed band size: 33 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Defects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 2 (PEOA2) [MIM:609283]. Progressive external ophthalmoplegia is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism. |
| Immunogen | KLH conjugated synthetic peptide: human ANT1/2/3/4 |
| Antigen Species | Human |
| Gene Name | SLC25A4 |
| Gene ID | |
| Protein Name | ADP/ATP translocase 1 |
| Uniprot ID | |
| Function | Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. |
| Molecular Weight | Theoretical: 33 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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